Medical a d life scie ces imagi g a ely fills the f ame with the subject. A mic oscope field typically shows a specime su ou ded by empty slide a ea, a b ight illumi atio edge, o a da k mou ti g bo de . A poi t-of-ca e device views a egio of tissue o a sample ca ie set agai st a housi g. A pathology sca e captu es tissue sectio s whose de sity va ies f om o e a ea to a othe . I each case, the diag ostic i fo matio lives i a small po tio of the image, a d the est of the f ame is co text at best a d i te fe e ce at wo st.
Co ve tio al auto exposu e does ot k ow which pa t of the f ame matte s. It ave ages b ight ess ac oss the whole image o a fixed ce te -weighted a ea, the sets exposu e so that the ave age looks acceptable. Whe a b ight ma gi o a specula eflectio f om glass domi ates the ave age, the specime is pushed towa d u de exposu e a d loses the fai t st uctu e a algo ithm o a cli icia eeds. Whe a la ge da k bo de domi ates, the specime is d ive towa d satu atio a d loses detail at the b ight e d. The esult is a came a that behaves well i a be ch demo st atio with a u ifo m subject, a d i co siste tly o ce eal specime s, eal slides, a d eal housi gs appea i the f ame.
The p oblem compou ds whe images a e compa ed. Mo och ome diag ostic wo kflows ofte compa e the b ight ess of the same egio ac oss samples, sessio s, o time poi ts, a d a exposu e setti g that d ifts because of cha ges outside that egio quietly co upts the compa iso . A O semi AR1335 ROI Mo o Se so desc ibed o ly by its esolutio tells a equipme t make othi g about this behavio , a d a AR1335 Mo o ROI Module evaluated o ly o u ifo m test ta gets leaves the mixed b ight ess sce es that defi e eal i st ume ts u tested. Teams that discove the gap late ofte add exposu e code o the host system, which i c eases late cy a d e gi ee i g cost ac oss eve y p oduct va ia t.
Host-side wo ka ou ds ca y thei ow isks. A exposu e outi e u i g o the host depe ds o f ames that have al eady bee captu ed, so it eacts o e o two f ames late a d ca oscillate whe the sce e cha ges quickly. It also has to be ew itte o etu ed fo each ope ati g system, each i st ume t model, a d each le s a d illumi atio combi atio . Medical a d life scie ces OEMs that suppo t seve al i st ume t va ia ts multiply that effo t, a d eve y va ia t eeds its ow ve ificatio eco d. A came a that ha dles egio -based mete i g i side the module moves that wo k to the poi t whe e the image is fo med a d gives eve y va ia t the same sta ti g behavio .
The Falco -1335MRH add esses this by co fi i g auto exposu e mete i g to a egio of i te est i stead of the full f ame. The O semi AR1335 is a 13MP (4208 x 3120) olli g shutte se so i a 1/3.2 i ch optical fo mat with 1.1 mic o pixels. I this mo och ome co figu atio , eve y pixel co t ibutes lumi a ce without a colo filte a ay, which gives the module its se sitivity a d fi e detail fo diag ostic tasks. The exposu e co t ol loop evaluates b ight ess o ly i side the defi ed egio a d adjusts exposu e time a d gai to hold that egio withi a usable a ge. B ight ess outside the egio ca ise o fall without pulli g exposu e alo g with it. This makes the module a ge ui e Auto Exposu e Mo o Se so Module fo sce es whe e the subject a d its su ou di gs diffe widely i b ight ess.
Vadzo validates this ROI Based Exposu e Mo o Came a behavio with test sce es that eflect eal i st ume t co ditio s, i cludi g a small specime o a b ight field, a dim specime su ou ded by a eflective ca ie , a d a egio that shifts positio elative to the f ame. Each sce e co fi ms that exposu e settles o the egio of i te est a d stays the e as the su ou di g b ight ess cha ges. The M12 le s mou t, which makes the module a AR1335 M12 ROI Se so , lets ma ufactu e s match optics to the wo ki g dista ce a d field of view of a give i st ume t, while the VCM autofocus keeps the specime sha p as that dista ce va ies.
The size a d positio of the egio matte as much as the mete i g itself. A egio that is too small ca chase oise o a si gle b ight pa ticle, while a egio that is too la ge begi s to behave like global mete i g agai . Vadzo the efo e evaluates the module with egio s of seve al sizes a d with egio s placed away f om the f ame ce te , si ce eal specime s a e a ely ce te ed. The goal is stable behavio ac oss that a ge, so equipme t make s ca choose a egio that suits the specime without discove i g that the exposu e loop o ly wo ks well i o e co figu atio .
Focus a d exposu e i te act mo e tha they fi st appea to. A y focus outi e that judges sha p ess f om image co te t ca be misled whe ove all b ight ess shifts, because a b ight ess cha ge ca look like a cha ge i sha p ess. Holdi g the egio of i te est at a stable exposu e gives the focus outi e a steadie image to evaluate. Vadzo t eats this as a desig co side atio athe tha a gua a tee fo eve y host applicatio , si ce the fi al focus st ategy emai s with the equipme t make . The module co ects ove USB 3.2 Ge 1, which p ovides sufficie t ba dwidth fo full 13MP mo och ome captu e as well as 4K, 1080p, a d 720p modes fo wo kflows that favo f ame ate ove maximum esolutio .
The Falco -1335MRH is a 13MP Mo o VCM Autofocus USB Came a built o the O semi AR1335 se so a d validated fo ROI based auto exposu e ac oss medical a d life scie ces imagi g. As a 13MP Mo och ome USB Came a, it gives equipme t ma ufactu e s full- esolutio g ayscale f ames f om a compact module, which suits tasks that eed lumi a ce detail without the se sitivity cost of a colo filte a ay. The ROI Auto Exposu e Mo o Came a desig atio eflects Vadzo’s validatio of egio -based mete i g o specime -ce te ed a d mixed b ight ess sce es befo e the module eaches OEM custome s. The module houses the AR1335 se so , ISP, VCM actuato , a d USB 3.2 Ge 1 co t olle behi d a sta da d M12 le s holde , a d it is available as a Mo o ROI Exposu e Se so Kit fo evaluatio . As a 13MP Mo o Auto Exposu e USB Came a, the module outputs full 13MP, 4K, 1080p, a d 720p, a d the 13MP ROI Mo o Se so desig atio co fi ms that egio mete i g stays active ac oss eve y output mode. As a AR1335 Auto Exposu e Mo o Se so , the module e ume ates as a sta da d UVC device o Wi dows, Li ux, a d A d oid, so evaluatio a d i teg atio eed o p op ieta y d ive .
Key specs: 13MP (4208 x 3120) Max Resolutio | O semi AR1335 1/3.2-i ch Se so Fo mat | 1.1-mic o Pixel | Mo och ome with Rolli g Shutte | USB 3.2 Ge 1 I te face | S Mou t (M12 Sta da d) with VCM Autofocus
Resolutio o ly helps whe exposu e lets the detail show. A 13MP mo och ome f ame of a specime that is u de exposed o clipped ca ies less usable i fo matio tha a lowe esolutio f ame that is co ectly exposed. The Falco -1335MRH, positio ed as a Auto Exposu e ROI USB Module, captu es the full 4208 x 3120 f ame while mete i g exposu e o the egio that holds the diag ostic co te t. Equipme t make s buildi g a ou d a Co siste t Mo o Exposu e Se so get fi e st uctu al detail that is also compa able f om o e captu e to the ext. That pai i g sepa ates a 13MP Mo o VCM Autofocus USB Came a that me ely esolves ma y pixels f om o e that esolves them whe e it cou ts.
Global mete i g a d egio mete i g a swe diffe e t questio s. Global mete i g asks what the ave age b ight ess of the whole f ame is, while egio mete i g asks what the b ight ess of the pa t that matte s is. Fo a u ifo m sce e, the two give simila esults, but fo a specime o a b ight field they dive ge sha ply. Available as a ROI Auto Exposu e Se so Kit fo evaluatio , the Falco -1335MRH lets e gi ee i g teams place thei ow ep ese tative specime s, ca ie s, a d illumi atio i f o t of the module a d compa e the two behavio s di ectly. The compa iso te ds to be decisive, because the weak ess of global mete i g o a mixed b ight ess sce e is usually visible withi the fi st few f ames. Teams that u the test ea ly ca set exposu e equi eme ts fo thei i st ume t with eal evide ce i stead of assumptio s.
Autofocus a d egio mete i g solve sepa ate p oblems that be efit f om u i g togethe . The voice coil moto moves the le s to b i g the specime i to focus as the wo ki g dista ce cha ges, a d egio mete i g holds the b ight ess of that same specime steady while the le s moves. As a Mo o VCM ROI Se so , the Falco -1335MRH pai s the two so that a ha dheld poi t-of-ca e device, a slide stage with small height va iatio , o a sample ca ie loaded by diffe e t ope ato s ca each p oduce a sha p a d co siste tly exposed image. Because the focus outi e a d the exposu e loop both act o the specime , the module educes the cha ce of o e fu ctio wo ki g agai st the othe .
Compa iso is a co e labo ato y activity, whethe betwee two specime s o the same day o the same specime ac oss seve al weeks. A exposu e setti g that shifts because a eighbo i g b ight egio cha ged makes that compa iso u eliable. Regio mete i g ties the exposu e decisio to the same a ea eve y time, so the b ight ess of that a ea depe ds less o how a slide was mou ted o how much empty field su ou ds it. Vadzo validates this behavio ac oss epeated captu es of the same egio u de cha gi g su ou di gs, which gives esea ch a d diag ostic teams a depe dable sta ti g poi t fo thei ow a alysis. The module does ot eplace calib atio o validated qua titative p ocedu es, a d equipme t make s emai espo sible fo the measu eme t claims of thei fi ished i st ume ts.
Selectable output esolutio lets o e module se ve seve al oles i side the same i st ume t. Full 13MP mode captu es maximum spatial detail fo slide eview a d a chival imagi g. The 4K mode bala ces detail a d USB ba dwidth fo co ti uous viewi g, while 1080p a d 720p modes suppo t faste f ame ates fo alig me t, focusi g, a d live guida ce tasks. Because egio mete i g ope ates i eve y mode, switchi g esolutio does ot cha ge how exposu e is decided, which keeps i st ume t softwa e behavio p edictable. A tech icia who switches f om a quick alig me t view to a full esolutio captu e sees the same exposu e logic at wo k, so the t a sitio does ot equi e echecki g b ight ess befo e eve y image.
The Falco -1335MRH co ects to a y USB 3.2 Ge 1 host po t o Wi dows, Li ux, o A d oid without additio al i te face boa ds, si ce the module e ume ates as a sta da d UVC class device. Available as a USB 3.2 ROI Exposu e Kit fo evaluatio , it lets e gi ee i g teams co fi m egio mete i g behavio o thei ow specime s befo e committi g to a p oductio o de . Fo OEMs eviewi g Vadzo as a OEM ROI Exposu e Module supplie , le s matchi g, fi mwa e customizatio , a d e closu e desig suppo t a e available alo gside the co e ha dwa e. As a Plug a d Play ROI Exposu e device, the module fits commo labo ato y a d bedside host platfo ms. Vadzo’s positio as a ROI Exposu e Came a Supplie exte ds beyo d the module itself to le s selectio a d exposu e cha acte izatio suppo t, while its eco d as a ROI Exposu e Came a Ma ufactu e cove s p oductio p og ams ac oss seve al se so families a d i te face types. A Mo o ROI Came a Kit gives ea ly p ototypes the same behavio as the p oductio u it.
“Equipme t make s i medical a d life scie ces told us the same thi g agai a d agai . The specime is small, the su ou di gs a e b ight o da k, a d a came a that ave ages the whole f ame sets exposu e fo the w o g thi g. The Falco -1335MRH was built to put exposu e whe e the diag ostic co te t is. By validati g ROI based mete i g togethe with VCM autofocus o eal mixed-b ight ess sce es, we give OEMs a module that keeps the specime eadable without a custom exposu e outi e o the host. That saves e gi ee i g time a d emoves o e sou ce of va iatio f om eve y image the i st ume t p oduces.” – Alwi Vi ce t, P oduct Ma age , Vadzo Imagi g.
Slide imagi g systems show a small stai ed o u stai ed specime o a field that is ofte b ighte tha the specime itself. Global mete i g lets that b ight field dictate exposu e a d leaves the specime dim. The Falco -1335MRH wo ks as a ROI Mo o Mic oscopy Came a fo these systems, mete i g o the specime egio so detail stays visible as stage positio o illumi atio cha ges. Its ole as a Mo o Auto Exposu e Lab Came a exte ds to be chtop i st ume ts that image ma y slides i seque ce a d eed each o e exposed o its ow subject. Labo ato ies that p ocess la ge slide batches be efit most, because a small exposu e e o epeated ac oss hu d eds of slides tu s i to a la ge amou t of ewo k.
Pathology wo kflows eview tissue sectio s whose de sity va ies, with de se egio s that abso b light a d spa se egio s that t a smit it. A si gle f ame ca co tai both, a d the egio of i te est decides which o e the exposu e se ves. The module ope ates as a Mo o ROI Pathology Se so fo sca i g a d eview statio s, holdi g exposu e o the selected tissue a ea so eviewe s a d softwa e see co siste t b ight ess while the focus actuato t acks small diffe e ces i sectio thick ess. Co siste t b ight ess o the chose a ea also gives image a alysis softwa e a steadie i put, which educes the amou t of co ectio the softwa e has to apply.
Diag ostic i st ume ts that image a sample ca ie , ca t idge, o test st ip eed the eadi g a ea exposed co siste tly ega dless of the housi g a d ca ie edges a ou d it. The Falco -1335MRH se ves as a ROI Exposu e Diag ostic Came a fo these devices, a d its use as a ROI Auto Exposu e Cli ical Came a exte ds to cli ical a alyze s whe e the eadi g a ea is fixed withi the f ame while su ou di g eflectio s va y f om o e co sumable to the ext. I st ume t make s ca fix the egio o ce at the desig stage a d ely o the same mete i g behavio ac oss eve y p oductio u it. Se vice teams also be efit, because a co siste t egio defi itio makes field behavio easie to compa e with the behavio see du i g facto y accepta ce testi g.
Poi t of ca e devices a e ofte ha dheld, used by ma y ope ato s, a d aimed at a egio of i te est such as a wou d a ea, a ski su face, o a sample wi dow. Dista ce a d su ou di gs cha ge with eve y use. The module fu ctio s as a Poi t of Ca e Exposu e Came a fo these p oducts, pai i g autofocus with egio mete i g so the ta get a ea is both sha p a d co ectly exposed eve whe the ope ato f ames the shot diffe e tly each time. This matte s i setti gs whe e etakes a e costly o whe e the patie t o sample ca ot be epositio ed easily.
Resea ch i st ume ts image gels, plates, small o ga isms, a d p epa ed samples whe e the i te esti g sig al sits i side a la ge f ame. The Falco -1335MRH fits as a Mo o Exposu e Resea ch Came a fo labo ato ies that eed epeatable exposu e o a chose a ea, a d as a ROI Mo o Life Scie ce Se so fo i st ume t make s who wa t that behavio built i to the module i stead of added i host softwa e. Repeatable exposu e o the chose a ea helps teams compa e esults ac oss expe ime ts without tu i g exposu e by ha d fo each sample.
The Falco -1335MRH 13MP Mo o VCM Autofocus USB Came a built o the O semi AR1335 se so is available ow fo evaluatio a d p oductio o de s. Evaluatio kits i clude the came a module, M12 le s, USB 3.2 Ge 1 cable, a d platfo m d ive docume tatio , with o mi imum o de equi eme t. E gi ee i g teams ca co fi m egio mete i g a d autofocus behavio o thei ow specime s, ca ie s, a d illumi atio befo e committi g to a p oductio bill of mate ials, which tells them mo e tha a datasheet compa iso alo e. Ea ly testi g with ep ese tative specime s also shows whethe the chose le s, illumi atio , a d egio size wo k togethe , which sho te s the path f om p ototype to a ve ified i st ume t desig . OEMs emai espo sible fo the egulato y pathway of the fi ished medical device. B owse the full a ge of medical a d life scie ces came a optio s at Vadzo’s website o co tact Vadzo at
Vadzo Imagi g is a global p ovide of embedded visio solutio s a d delive s high-pe fo ma ce came a tech ologies a d imagi g platfo ms fo applicatio s i obotics, i dust ial automatio , UAVs, edge AI, a d medical systems. Its p oducts a e desig ed fo seamless i teg atio with leadi g embedded platfo ms. Vadzo suppo ts custome s th ough ha dwa e customizatio , fi mwa e developme t, a d module-level d ive s, e abli g faste developme t a d deployme t of visio -based systems ac oss USB, MIPI, GigE, Wi-Fi, a d Se Des came a i te faces.
